Which poppy seeds contain opium
Besides the medical importance of opium poppy, the plant also plays a role in the domain of food. The mature seeds are used predominantly in poppy cakes but also in smaller amounts on rolls and bagels. Because of their high oil content, edible oil is produced from the seeds, too. Although the seeds may also contain alkaloids, they only occur naturally in traces.
Hence, edible poppy seeds are only likely to contain the smallest amounts of morphine. Studies on alkaloid levels in edible poppy seeds have, however, revealed that the levels vary markedly and have increased overall in recent years.
Types of poppy, harvesting time and geographical origin could all influence the alkaloid levels. The main reason for the increase seems, however, to be the contamination of the seeds with alkaloid-containing capsule fragments or the milky sap itself. Possible causes under discussion are recently introduced harvesting methods in which the capsules are squashed and the milky sap released could contaminate the seeds. In unfavourable circumstances, normal consumption of poppy seed-containing foods could lead to the ingestion of morphine amounts which are in the therapeutic range.
The overall range of adverse reactions could then occur. They include central nervous and peripheral effects like impaired consciousness, respiratory disorders and cardiovascular effects. It is clear that highly contaminated poppy seeds are dangerous and not suited for placement on the market or consumption. The health assessment of the consumption of poppy seeds with low morphine concentrations is more difficult from the precautionary angle.
It is 6. Food Chem. Gumuscu, A. Evaluation of selected poppy Papaver somniferum L. Eur Food Res Technol. International Narcotics Board Effect of poppy seed consummation on the positive results of opiates screening in biological samples. Legal Med. Kapoor, L. Opium Poppy: Botany, Chemistry and Pharmacology.
Katrine, K. Update of the scientific opinion on opium alkaloids in poppy seeds. Koleva, I. Alkaloids in the human food chain — Natural occurrence and possible adverse effects.
Food Res. Krenn, L. Determination of the five major opium alkaloids by reversed-phase high-performance liquid chromatography on a base-deactivated stationary phase. Chromatographia 47, 21— Lachenmeier, D.
Poppy seed foods and opiate drug testing - where are we today? Drug Monit. Lahiri, R. Genetic variability and diversity in Indian germplasm of opium poppy Papaver somniferum L.
Plants 8, 41— Straightforward analytical method to determine opium alkaloids in poppy seeds and bakery products. Mahdavi-Damghani, A. Water stress effects on growth, development and yield of opium poppy Papaver somniferum L. Water Manag. The history of opiates. Meadway, C. Opiate concentrations following the ingestion of poppy seed products - evidence for 'the poppy seed defence'.
Forensic Sci. Miller, R. More mysteries of opium revealed: years of opiates. Trends Pharmacol. Moeller, M. Poppy seed consumption and toxicological analysis of blood and urine samples. Mohsin, H. The chemical investigation of Papaver seeds. CrossRef Full Text. Panicker, S. Quantitation of the major alkaloids in opium from Papaver setigerum. Microgram J. Rohrig, T. The determination of morphine in urine and oral fluid following ingestion of poppy seeds. Schiff, P. Opium and its alkaloids.
Smith, M. Morphine and codeine concentrations in human urine following controlled poppy seeds administration of known opiate content. Sproll, C. Guidelines for reduction of morphine in poppy seed intended for food purposes.
Stermitz, F. The biosyntheis of opium alkaloids. Alkaloid Interconversions in Papaver somniferum and P. Stranska, I. Analysis of selected poppy Papaver somniferum L. Crops Prod. Windle, J. Harms caused by China's —17 opium suppression intervention. Drug Policy. Wong, R. Oral fluid drug tests: effects of adulterants and foodstuffs. Yoshimatsu, K. A rapid and reliable solid-phase extraction method for high-performance liquid chromatographic analysis of opium alkaloids from Papaver plants.
The use, distribution or reproduction in other forums is permitted, provided the original author s and the copyright owner s are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. Carlin, m. Dean and Jennifer M. Introduction Papaver somniferum L. Figure 1. Chemical structures of the major opium alkaloids.
Table 2. Poppy seed source and country of origin. Table 3. Mobile phase composition and gradient program for HPLC. Table 6. Extraction solvents and associated polarity index values. Table 7. Table 9. Services for applicants Toolkit Track your application Event calendar Ask a question. Grants Calls for data Consultations Observers. Stakeholders Engagement platforms Engagement in risk assessment Calls for stakeholders Stakeholder registration Training Programme.
Funding programmes Upcoming calls Knowledge Centre National funding opportunities. Opium alkaloids in poppy seeds: assessment updated. Published :. Data gaps The assessment also considered data on other alkaloids present in poppy seeds — thebaine, oripavine, noscapine and papaverine.
What is an acute reference dose? In brief: opium alkaloids in poppies Poppy seeds are obtained from the opium poppy Papaver somniferum. The latex milky sap of the opium poppy contains up to 80 alkaloids, including morphine and codeine, which have been used for the treatment of severe pain for generations but are also subject to misuse. The seeds are used as food and to produce edible oil.
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